✦ LIBER ✦

Paroxysmal nocturnal hemoglobinuria terminating as erythroleukemia

✍ Scribed by David E. Cowall; Dominick N. Pasquale; Paul Dekker

Publisher: John Wiley and Sons
Year: 1979
Tongue: English
Weight: 591 KB
Volume: 43
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(197905)43:5<1914::aid-cncr2820430549>3.0.co;2-q

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✦ Synopsis

A case of a patient who developed erythroleukemia 3 years into the course of paroxysmal nocturnal hemoglobinuria (PNH) is presented. A case of erythroleukemia with a positive sucrose lysis test has been reported, but our case appears to be the first with a long clinical course of PNH evolving into erythroleukemia. The association between these two diseases, their possible clonal origin, and how they fit into the myelodysplastic syndromes are discussed.

Cancer 43:1914-1916, 1979.

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