Paroxysmal nocturnal hemoglobinuria (PNH) is a rare clonal stem-cell disorder in which blood cells lack complement inhibiting membrane proteins, and become susceptible to complement-mediated injury, leading to chronic intravascular hemolysis and pancytopenia. Glucocorticoids have been a mainstay of
โฆ LIBER โฆ
Corticosteroids therapy in paroxysmal nocturnal hemoglobinuria
โ Scribed by Dr. Surapol Issaragrisil; Anong Piankijagum; Yaowalak Tang-naitrisorana
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 421 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0361-8609
No coin nor oath required. For personal study only.
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A case of a patient who developed erythroleukemia 3 years into the course of paroxysmal nocturnal hemoglobinuria (PNH) is presented. A case of erythroleukemia with a positive sucrose lysis test has been reported, but our case appears to be the first with a long clinical course of PNH evolving into e