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Paroxysmal nocturnal haemoglobinuria : Peri-operative management of a patient with Budd-Chiari syndrome

✍ Scribed by M. B. TAYLOR; J. G. WHITWAM; A. WORSLEY


Book ID
108619743
Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
321 KB
Volume
42
Category
Article
ISSN
0003-2409

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Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired hemolytic anemia caused by somatic mutations in the phosphatidylinositol glycan-complementation class A gene and the resulting absence of a key complement regulatory protein, CD59. Affected red blood cells in patients with PNH undergo int