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Parkisonism induced by high-dose cytosine arabinoside

✍ Scribed by Dr. F. Antonio Luque; John B. Selhorst; Paul Petruska

Publisher: John Wiley and Sons
Year: 1987
Tongue: English
Weight: 280 KB
Volume: 2
Category: Article
ISSN: 0885-3185
DOI: 10.1002/mds.870020309

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✦ Synopsis

We report a severe parkinsonian condition following high dose, parenteral cytosine arabinoside (Cytosar) that persisted for 8 weeks. The drug was used in a patient with acute myelogenous leukemia that was refractory to all other treatment. The syndrome was partially responsive to antiparkinsonian drugs and fortunately remitted completely within 12 weeks.

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