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Parkinson's disease, pesticides, and glutathione transferase polymorphisms

✍ Scribed by Alessandra Menegon; Philip G Board; Anneke C Blackburn; George D Mellick; David G Le Couteur

Book ID: 117311273
Publisher: The Lancet
Year: 1998
Tongue: English
Weight: 67 KB
Volume: 352
Category: Article
ISSN: 0140-6736
DOI: 10.1016/s0140-6736(98)03453-9

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## Abstract Monogenic forms of Parkinson's disease (PD) provide an opportunity to examine mechanisms underlying phenotypic variation. Glutathione S‐transferase (GST) has detoxification and antioxidative functions. To screen genetic variations in GST for an effect on the onset age (OA) of PD, we typ