Glutathione transferase polymorphism and Parkinson's disease
β Scribed by Moreno Paolini; Gian Luigi Biagi; Giorgio Cantelli-Forti
- Book ID
- 117294292
- Publisher
- The Lancet
- Year
- 1999
- Tongue
- English
- Weight
- 40 KB
- Volume
- 353
- Category
- Article
- ISSN
- 0140-6736
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π SIMILAR VOLUMES
## Abstract Monogenic forms of Parkinson's disease (PD) provide an opportunity to examine mechanisms underlying phenotypic variation. Glutathione Sβtransferase (GST) has detoxification and antioxidative functions. To screen genetic variations in GST for an effect on the onset age (OA) of PD, we typ
## Abstract We studied genetic polymorphisms in the glutathioneβ__S__βtransferaseβ1 (GSTβ1) gene region and the interleukinβ1Ξ² (ILβ1Ξ²) promoter region in patients with Parkinson's disease (PD, n = 361), as well as controls (n = 257). Although we have confirmed the previous results, in a larger samp