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Parental transmission ofHLA-DRB1*15in multiple sclerosis

✍ Scribed by Sreeram V. Ramagopalan; Blanca M. Herrera; Jordana T. Bell; David A. Dyment; Gabriele C. DeLuca; Matthew R. Lincoln; Sarah M. Orton; Michael J. Chao; A. Dessa Sadovnick; George C. Ebers

Publisher: Springer
Year: 2007
Tongue: English
Weight: 194 KB
Volume: 122
Category: Article
ISSN: 0340-6717
DOI: 10.1007/s00439-007-0442-z

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## Abstract Susceptibility to multiple sclerosis (MS) is associated genetically with human leucocyte antigen (HLA) class II alleles, including DRB1\*1501, DRB5\*0101, and DQB1\*0602, and it is possible that these alleles contribute to MS through an enhanced ability to present encephalitogenic myeli