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HLA-DRB1 and disease outcome in multiple sclerosis

✍ Scribed by S. J. M. Weatherby; W. Thomson; L. Pepper; R. Donn; J. Worthington; C. L. A. Mann; M. B. Davies; A. A. Fryer; M. D. Boggild; C. A. Young; P. W. Jones; R. C. Strange; W. E. R. Ollier; C. P. Hawkins


Publisher
Springer
Year
2001
Tongue
English
Weight
225 KB
Volume
248
Category
Article
ISSN
0340-5354

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## Abstract Susceptibility to multiple sclerosis (MS) is associated genetically with human leucocyte antigen (HLA) class II alleles, including DRB1\*1501, DRB5\*0101, and DQB1\*0602, and it is possible that these alleles contribute to MS through an enhanced ability to present encephalitogenic myeli