Paraneoplastic pemphigus (PNP) is an autoimmune disorder occurring in the setting of an underlying neoplasm in which patients have polymorphous skin and mucous membrane lesions. We describe a patient with non-Hodgkin's lymphoma who developed bullous, ulcerating lesions in an area being treated with
Paraneoplastic movement disorder in a patient with non-Hodgkin's lymphoma and CRMP-5 autoantibody
β Scribed by Ali Samii; Debra D. Dahlen; Alexander M. Spence; Nicole C. Maronian; Eric E. Kraus; Vanda A. Lennon
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 49 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0885-3185
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β¦ Synopsis
Abstract
The paraneoplastic autoantibody, collapsin responseβmediator protein (CRMP)β5 immunoglobulin G (IgG), is specific for neuronal cytoplasmic CRMPβ5, and is usually associated with smallβcell lung carcinoma or thymoma. We report on details of a movement disorder that followed antiβBβcell therapy in a patient with lymphoma, and was accompanied by CRMPβ5 IgG. Β© 2003 Movement Disorder Society
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