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Paraneoplastic pemphigus in a patient with non-Hodgkin's lymphoma

✍ Scribed by Plumb, Renee; Doolittle, Gary C.

Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
259 KB
Volume
52
Category
Article
ISSN
0361-8609

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✦ Synopsis

Paraneoplastic pemphigus (PNP) is an autoimmune disorder occurring in the setting of an underlying neoplasm in which patients have polymorphous skin and mucous membrane lesions.

We describe a patient with non-Hodgkin's lymphoma who developed bullous, ulcerating lesions in an area being treated with radiation therapy. The diagnosis of PNP was confirmed by indirect immunofluorescence of the patient's serum on rat bladder. The disorder was refractory to therapy, and ultimately the patient expired.

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