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Ph chromosome in a patient with non-leukemic non-hodgkin B-cell lymphoma

✍ Scribed by Hiroshi Fujii; Hiromi Yashige; Shinichi Misawa; Shinji Tanaka; Yohji Urata; Fumio Matuyama


Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
294 KB
Volume
35
Category
Article
ISSN
0361-8609

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✦ Synopsis


A standard Philadelphia translocation, t(9;22) (q34;qll), was found In lymph node cells from a patient with non-leukemic non-Hodgkln lymphoma at the time of diagnosis. The rearrangement of the breakpoint cluster region (bcr) was not detected with a bcr-3' probe, The neoplastic clone was of monoclonal B-cell character with E-, CD5-, CDlO-, CD13-, CD19t, CDZOt, CD21+, CD255, HLA DRt, and positive surface Ig(kappa). The patient showed no evidence of chronic myelogenous leukemia.


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