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Parallel Synthesis of Arrays of Amino-Acid-Derived Isocyanoamides Useful As Starting Materials in IMCR

✍ Scribed by Dömling, Alexander; Beck, Barbara; Fuchs, Thilo; Yazbak, Ahmad


Book ID
126451852
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
186 KB
Volume
8
Category
Article
ISSN
1520-4766

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✍ Martin Ostendorf; Jan Dijkink; Floris P. J. T. Rutjes; Henk Hiemstra 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 398 KB 👁 2 views

The synthesis of four enantiopure hydroxyamidines is amidine was obtained by coupling of an (S)-malic acid derived N-acyliminium ion with β-naphthol. The other described. One amidine was obtained from (S)-pyroglutamic acid. Its key step involved the addition of phenylmagnesium amidines were obtained