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Preparation of chiral derivatives of β-Ala containing the α-phenylethyl group: useful starting materials for the asymmetric synthesis of β-amino acids

✍ Scribed by Guzmán-Mejía, Ramón; Reyes-Rangel, Gloria; Juaristi, Eusebio


Book ID
109946321
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
369 KB
Volume
2
Category
Article
ISSN
1750-2799

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Enantioselective Synthesis of β-Amino Ac
✍ Víctor Manuel Gutiérrez-García; Gloria Reyes-Rangel; Omar Muñoz-Muñiz; Eusebio J 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 German ⚖ 129 KB

## Abstract Inexpensive acryloyl chloride was converted in 91% overall yield to two derivatives of __β__‐alanine, (__R__,__R__,__R__)‐**6** and (__R__,__R__,__S__)‐**6**, containing two chiral auxiliaries. __C__‐Alkylation of (__R__,__R__,__R__)‐ and (__R__,__R__,__S__)‐**6** __via__ a dianion deri