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Enantioselective synthesis of β-amino acids. Part 11: Diastereoselective alkylation of chiral derivatives of β-aminopropionic acid containing the α-phenethyl group

✍ Scribed by Vı́ctor Manuel Gutiérrez-Garcı́a; Heraclio López-Ruiz; Gloria Reyes-Rangel; Eusebio Juaristi


Book ID
108371264
Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
242 KB
Volume
57
Category
Article
ISSN
0040-4020

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Enantioselective Synthesis of β-Amino Ac
✍ Víctor Manuel Gutiérrez-García; Gloria Reyes-Rangel; Omar Muñoz-Muñiz; Eusebio J 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 German ⚖ 129 KB

## Abstract Inexpensive acryloyl chloride was converted in 91% overall yield to two derivatives of __β__‐alanine, (__R__,__R__,__R__)‐**6** and (__R__,__R__,__S__)‐**6**, containing two chiral auxiliaries. __C__‐Alkylation of (__R__,__R__,__R__)‐ and (__R__,__R__,__S__)‐**6** __via__ a dianion deri