The synthesis of four enantiopure hydroxyamidines is amidine was obtained by coupling of an (S)-malic acid derived N-acyliminium ion with Ξ²-naphthol. The other described. One amidine was obtained from (S)-pyroglutamic acid. Its key step involved the addition of phenylmagnesium amidines were obtained
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ChemInform Abstract: (S)-Pyroglutamic Acid, (S)-Malic Acid, and (S)-Serine as Useful Starting Materials in the Synthesis of Enantiopure Hydroxyamidines.
β Scribed by Martin Ostendorf; Jan Dijkink; Floris P. J. T. Rutjes; Henk Hiemstra
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 32 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0931-7597
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