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Parallel Solid-Phase Synthesis of Trisubstituted Triazinobenzimidazolediones

✍ Scribed by Klein, Gérard; Acharya, Achyuta N.; Ostresh, John M.; Houghten, Richard A.


Book ID
121433667
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
67 KB
Volume
4
Category
Article
ISSN
1520-4766

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Solid-phase synthesis of trisubstituted
✍ David H. Drewry; Samuel W. Gerritz; James A. Linn 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 233 KB

The solid-phase synthesis of trisubsituted guanidines is reported via aza-Wittig coupling of a solid-supported alkyl iminophosphorane with an aryl or alkyl isothiocyanate to generate the corresponding solid-supported carbodiimide which is then reacted with a primary or secondary amine to afford the