Sera from hamsters bearing tumors induced by papovavirus SV40 reacted with tumor antigen prepared either from cells transformed by, or from cells infected with, the homologous virus. Serum titers against both antigens were comparable. A high degree of correlation was obtained with the use of either
โฆ LIBER โฆ
Papovavirus SV40: Failure to isolate infectious virus from transformed hamster cells synthesizing SV40-induced antigens
โ Scribed by Melnick, Joseph L.; Khera, Kundan S.; Rapp, Fred
- Book ID
- 123204225
- Publisher
- Elsevier Science
- Year
- 1964
- Tongue
- English
- Weight
- 283 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0042-6822
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## Abstract The immunogenicity of the SV40 tumorโspecific transplantation antigen (TSTA) on cells, cell particulates and solubilized membranes was studied in mice and in Syrian hamsters. Immunizations were done with various concentrations of tissueโcultureโpassaged, nonโvirusโreleasing transformed