Papain Catalysed Hydantoin Hydrolysis in the Synthesis of Amino Acids
β Scribed by Rekha Rai; Veena Taneja
- Book ID
- 115581839
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 87 KB
- Volume
- 244
- Category
- Article
- ISSN
- 0006-291X
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π SIMILAR VOLUMES
Haake and Tyssee' postulated a dissociative (Al or Al-like) mechanism for the acidcatalysed hydrolysis of diphenylphosphinanilides 1. They considered cleavage of theP-N bond in the protonated anilide to be well advanced in the transition state 2 and nucleophilic participation by water to be small. A
## The synthesis of a,a-di&ylated amino acids which contain two adenine or thymine residues in their side chains is presented. In this context, a mild method for the cleavage of hydantoins is introduced. In nature only nucleic acids are capable of molecular replication. Some time ago,1 we demonstr