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Synthesis of α,α-dialkylated amino acids with adenine or thymine residues a new mild and facile hydrolysis of hydantoins

✍ Scribed by Stefan Kubik; Robert S. Meissner; Julius Rebek Jr.


Publisher
Elsevier Science
Year
1994
Tongue
French
Weight
259 KB
Volume
35
Category
Article
ISSN
0040-4039

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✦ Synopsis


The synthesis of a,a-di&ylated amino acids which contain two adenine or thymine residues in their side chains is presented. In this context, a mild method for the cleavage of hydantoins is introduced.

In nature only nucleic acids are capable of molecular replication. Some time ago,1 we demonstrated that relatively simple synthetic molecules could also show this behavior.


📜 SIMILAR VOLUMES


Hydrolysis of di-substituted hydantoins,
✍ R. Rai; R. Balaji Rao; V. Taneja 📂 Article 📅 1996 🏛 Springer 🌐 English ⚖ 384 KB

Hydrolysis of 5,5'-di-substituted hydantoins with linear and cyclic side chains, to produce the corresponding α,α-dialkylated amino acids and 1-aminocycloalkane-1-carboxylic acids, using an enzyme preparation from lentil (Lens esculenta) seeds is reported for the first time. This method could be dev