Palladium-catalyzed α-arylation of aldehydes with aryl bromides

✍ Scribed by Yoshito Terao; Yuichi Fukuoka; Tetsuya Satoh; Masahiro Miura; Masakatsu Nomura

• Book ID: 104232121
• Publisher: Elsevier Science
• Year: 2002
• Tongue: French
• Weight: 89 KB
• Volume: 43
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)02077-9

✦ Synopsis

Aliphatic linear and a-branched aldehydes efficiently undergo arylation at the a-position upon treatment with aryl bromides using an appropriate palladium catalyst system that is capable of overcoming aldol condensation of the substrates.