Palladium-catalyzed synthesis of quinolines from allylic alcohols and o-iodoaniline
β Scribed by Richard C. Larock; Mann-Yan Kuo
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- French
- Weight
- 237 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
## Abstract Treatment of allylic alcohols containing a 1,1βdisubstituted alkene with a palladium catalyst and hydrogen gas (1β bar) results in facile isomerization to their corresponding trisubstituted (__E__)βallylic alcohols, along with small amounts of the corresponding hydrogenated products.
Ally1 diethyl phosphates (\_1) can be easily substituted with malonates and amines in the presence of palladium(O) catalyst. Synthetic utility of the reaction is demonstrated by the sequential amination-amination and alkylation-amination of (Z)-4-acetoxybut-2-enyl diethyl phosphate Cl,b) with high r
## Abstract For Abstract see ChemInform Abstract in Full Text.