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Palladium-Catalyzed N-Monoarylation of Amidines and a One-Pot Synthesis of Quinazoline Derivatives

โœ Scribed by McGowan, Meredeth A.; McAvoy, Camille Z.; Buchwald, Stephen L.

Book ID
120351980
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
275 KB
Volume
14
Category
Article
ISSN
1523-7060

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One-pot synthesis of tetrahydrofuran der
One-pot synthesis of tetrahydrofuran derivatives via a divalent palladium-catalyzed three-component coupling
โœ Guosheng Liu; Xiyan Lu ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 326 KB

Under divalent palladium catalysis, a three-component coupling reaction for synthesizing tetrahydrofuran derivatives has been established. The reaction involves the intramolecular carbopalladation of an alkyne with a carbanion which was generated from the addition of an alkoxide ion to an alkene der