Palladium-catalyzed chemistry of .beta.-lactam vinyl triflates: coupling with organostannanes and alkoxycarbonylation
โ Scribed by Cook, Gwendolyn K.; Hornback, William J.; Jordan, Chris L.; McDonald, John H.; Munroe, John E.
- Book ID
- 126980061
- Publisher
- American Chemical Society
- Year
- 1989
- Tongue
- English
- Weight
- 428 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0022-3263
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๐ SIMILAR VOLUMES
The palladium-catalyzed coupling reaction of aryl triflates with alkyl, vinyl, acetylenic, and aryl tin reagents in the presence of lithium chloride takes place in high yields under mild conditions. However, allyltrialkyltin reagents coupled in lower yields, and unselective transfer of the allyl gro
En01 triflates l-5, derived from the corresponding dicarbonyl compound, were coupled with tin reagents 6-8 using Pd(OAc), and PPh, as the catalyst, at 7 mole %, in 56-Y 1% yield. Substituted u$ unsaturated esters, such as B, are functional moieties common to several natural products1 as well as use