Palladium(II)-catalyzed coupling of 2-carboxyethyl enol triflates with organostannanes.

✍ Scribed by Ioannis N. Houpis

• Publisher: Elsevier Science
• Year: 1991
• Tongue: French
• Weight: 257 KB
• Volume: 32
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)93572-x

✦ Synopsis

En01 triflates l-5, derived from the corresponding dicarbonyl compound, were coupled with tin reagents 6-8 using Pd(OAc), and PPh, as the catalyst, at 7 mole %, in 56-Y 1% yield.

Substituted u$ unsaturated esters, such as B, are functional moieties common to several natural products1 as well as useful precursors to sp3 quatemary centers and, when R= vinyl, Diels-Alder d&es.