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Palladium-Catalyzed Carbonylation of Yne Esters Leading to γ-Alkylidene α,β-Unsaturated γ-Lactones

✍ Scribed by Harada, Yasuyuki; Fukumoto, Yoshiya; Chatani, Naoto


Book ID
127229824
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
61 KB
Volume
7
Category
Article
ISSN
1523-7060

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e-Acetoxy-8,y-unsaturated nitriles react at room temperature with malonates and acetoacetates in the presence of palladium-phosphine complexes as a catalyst to give y-substituted a,8-unsaturated nitriles selectively. Also yacetoxy-a,8-unsaturated ester was attacked at y-position by malonate.