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Palladium-Catalyzed Carbonylation of Yne Esters Leading to γ-Alkylidene α,β-Unsaturated γ-Lactones.

✍ Scribed by Yasuyuki Harada; Yoshiya Fukumoto; Naoto Chatani


Book ID
111699597
Publisher
John Wiley and Sons
Year
2006
Weight
24 KB
Volume
37
Category
Article
ISSN
0931-7597

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e-Acetoxy-8,y-unsaturated nitriles react at room temperature with malonates and acetoacetates in the presence of palladium-phosphine complexes as a catalyst to give y-substituted a,8-unsaturated nitriles selectively. Also yacetoxy-a,8-unsaturated ester was attacked at y-position by malonate.