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P958. Analysis of mutations in p53 gene and detection of increased levels of p53 protein in women with sporadic or familial breast cancer

✍ Scribed by C. Napal; M. García-Delgado; C.J. González-Navarro; C. Baldonado; J.M. Lera; A. Gullón; J.L. Alcázar; G. López-García

Book ID
114316950
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
299 KB
Volume
6
Category
Article
ISSN
0960-9776

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Association among p53 gene mutation, nuc
Association among p53 gene mutation, nuclear accumulation of the p53 protein and aggressive phenotypes in breast cancer
✍ Hitoshi Tsuda; Setsuo Hirohashi 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 French ⚖ 855 KB

## Abstract In order to reveal whether differences in the type and site of __p53__ gene mutations influence the function of the gene and tumor phenotype, we examined nuclear accumulation of the p53 protein immunohistochemically, loss of the other p53 allele by restriction‐fragment‐length polymorphi