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Screening for germline mutations of the p53 gene in familial breast cancer patients

✍ Scribed by U. A. PATEL; M. PERRY; C. CRANE-ROBINSON

Book ID
114727405
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
820 KB
Volume
25
Category
Article
ISSN
0014-2972

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Germline mutations in the BRCA2 gene have been shown to be associated with familial female and male breast cancer. Mutations occur throughout the entire coding region of the gene, and there is considerable ethnic and geographical diversity in the deleterious mutations detected in different populatio