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p53 Expression in Gastric Cancer (Clinicopathological Correlation and Prognostic Significance)

✍ Scribed by S.P. Monig; S. Eidt; T.K. Zirbes; D. Stippel; S.E. Baldus; H. Pichlmaier


Book ID
110377227
Publisher
Springer US
Year
1997
Tongue
English
Weight
272 KB
Volume
42
Category
Article
ISSN
0163-2116

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The overexpression of the tumor suppressor gene p53 was investigated immunohistochemically in 144 cases of primary colorectal cancer and in 8 cases with cancer in the corresponding metastatic lymph nodes. Abnormalities in p53 expression were found in 36 cases (25%) of the 144 primary cancer cases. I