p53 and p21WAF1/CIP1 overexpression at the invasive front of lower lip squamous cell carcinoma
✍ Scribed by Martinho Campolina Rebello Horta; Luis Alpino Prandini De Assis; Antonio Francisco De Souza; Vera Cavalcanti De Araújo; Ricardo Santiago Gomez; Maria Cássia Ferreira Aguiar
- Book ID
- 111255014
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 637 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0904-2512
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
BACKGROUND. The clinical course of laryngeal squamous cell carcinoma (LSCC) varies considerably among patients. New biologic markers are needed to facilitate the stratification of individual patients within the conventional clinicopathologic stages of LSCC. METHODS. Eighty-three LSCCs from an equal
p21 WAF1/Cip1 is a recently identified gene involved in cell cycle regulation through cyclin-CDK-complex inhibition. The expression of this gene in several cell lines seems to be induced by wild-type, but not mutant, p53. p21 WAF1/Cip1 expression has been studied at both mRNA and protein levels in a