P4F147 - Deficiency of GST and NAT genes and risk of bladder cancer and schistosomiasis
β Scribed by K. Mitrunen; M.A. Watson; D.A. Bell; W. Anwar; A. Hirvonen
- Book ID
- 119540686
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 143 KB
- Volume
- 95
- Category
- Article
- ISSN
- 0378-4274
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## Abstract Tobacco smoking and occupation are major risk factors of bladder cancer via exposure to polycyclic aromatic hydrocarbons (PAHs) and aromatic amines. Glutathione Sβtransferase (GST) M1, T1 and P1 are involved in the detoxification of PAH reactive metabolites. Two __N__βacetyltransferase
In Egypt and other regions of the Middle East where the trematode Schistosoma haematobium is endemic, bladder cancer is the most common adult cancer. Unlike bladder cancers in Western countries, which are predominantly transitional-cell carcinoma (TCC), these schistosomiasisassociated bladder cancer