Combined effects of p73 and MDM2 polymor
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Hee Jung Jun; Sun Ha Park; Won Kee Lee; Jin Eun Choi; Jin Sung Jang; Eun Jin Kim
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Article
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2007
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John Wiley and Sons
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English
β 101 KB
## Abstract p73, a structural and functional homologue of p53, plays an important role in modulating cellβcycle control and apoptosis. MDM2 represses the transcriptional activity of p73 and thus attenuates its activity. Based on the interaction between p73 and MDM2 in cellβcycle control and apoptos