Impact of hemochromatosis gene (HFE) mut
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Philippe O. Gannon; Sanae Medelci; CΓ©cile Le Page; Martin Beaulieu; Diane M. Pro
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Article
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2010
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John Wiley and Sons
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French
β 281 KB
π 1 views
## Abstract Cancer cells require large amounts of micronutrients, particularly iron, for their rapid growth and frequent divisions. Cellular iron uptake is regulated by the transferrin receptor and the hemochromatosis protein (HFE) system. Two frequent mutations in the __HFE__ gene, H63D and C282Y,