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A case–control study on the effect of p53 and p73 gene polymorphisms on gastric cancer risk and progression

✍ Scribed by Emma De Feo; Roberto Persiani; Antonio La Greca; Rosarita Amore; Dario Arzani; Stefano Rausei; Domenico D’Ugo; Paolo Magistrelli; Cornelia M. van Duijn; Gualtiero Ricciardi; Stefania Boccia


Book ID
116759591
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
165 KB
Volume
675
Category
Article
ISSN
1383-5718

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Combined effects of p73 and MDM2 polymor
✍ Hee Jung Jun; Sun Ha Park; Won Kee Lee; Jin Eun Choi; Jin Sung Jang; Eun Jin Kim 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 101 KB

## Abstract p73, a structural and functional homologue of p53, plays an important role in modulating cell‐cycle control and apoptosis. MDM2 represses the transcriptional activity of p73 and thus attenuates its activity. Based on the interaction between p73 and MDM2 in cell‐cycle control and apoptos