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p38 Mitogen-Activated Protein Kinase Inhibitors— Mechanisms and Therapeutic Potentials

✍ Scribed by John C. Lee; Shouki Kassis; Sanjay Kumar; Alison Badger; Jerry L. Adams


Book ID
114129547
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
267 KB
Volume
82
Category
Article
ISSN
0163-7258

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Inhibitors of p38 mitogen-activated prot
✍ Sonja Horstmann; Philipp J. Kahle; Gian Domenico Borasio 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 253 KB 👁 2 views

Mammalian mitogen-activated protein kinases include the extracellular signal-regulated protein kinase, the c-Jun amino-terminal kinase, and the p38 subgroups. Sustained activation of Jun kinase and p38 have been shown to precede apoptosis of PC12 pheochromocytoma cells induced by withdrawal of troph