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P3.129 Genetic polymorphism of nicotinic acetylcholine receptor a4 subunit is associated with Parkinson's disease

✍ Scribed by E. Lyros; A. Papachatzopoulou; L. Messinis; P. Papathanasopoulos; A. Athanassiadou


Book ID
117753896
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
64 KB
Volume
15
Category
Article
ISSN
1353-8020

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The ␣4 subunit gene of the neuronal nicotinic acetylcholine receptor (CHRNA4) has recently been identified as the first gene underlying an idiopathic partial epilepsy syndrome in human, autosomal-dominant nocturnal frontal lobe epilepsy (ADNFLE). CHRNA4 is located in the candidate region for benign