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P3-209: Genetic variation in the alpha 7 nicotinic acetylcholine receptor is associated with delusional symptoms in Alzheimer's disease

✍ Scribed by Carson, Robyn; Craig, David; Hart, Dominic; Johnston, Janet A.; O'Neill, Francis A.; Passmore, A. Peter

Book ID
121955976
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
56 KB
Volume
4
Category
Article
ISSN
1552-5260

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## Abstract Alzheimer's disease (AD) and dementia with Lewy bodies (DLB) are common forms of dementia in the elderly associated with cholinergic dysfunction, including reductions in nicotinic acetylcholine receptors (nAChRs). In AD, astrocytes are implicated in the formation of senile plaques, one