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P.2.f.019 Effect of CYP2D6*10 polymorphism on mirtazapine metabolism in Japanese psychiatric patients

✍ Scribed by Watanabe, T.; Hyashi, Y.; Aoki, A.; Ishiguro, S.; Inoue, Y.; Akiyama, K.; Tsuchimine, S.; Yasui-Furukori, N.; Shimoda, K.

Book ID
126548446
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
77 KB
Volume
24
Category
Article
ISSN
0924-977X

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## Abstract ## Objective Risperidone is converted to 9‐hydroxyrisperidone by CYP2D6. Two parameters were used to examine the influences of CYP2D6 polymorphism and of co‐medication on risperidone metabolism: the risperidone:9‐hydroxyrisperidone concentration ratio (R:9‐OHR ratio) and the sum of the