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Polymorphic drug metabolism (CYP2D6) and utilisation of psychotropic drugs in hospitalised psychiatric patients: a retrospective study

✍ Scribed by Wim J. Tamminga; Johan Wemer; Berend Oosterhuis; Anthonius de Boer; Stan Vranckx; Ben F. H. Drenth; Rokus A. de Zeeuw; Lou F. M. H. de Leij; Jan H. G. Jonkman

Book ID
105920801
Publisher
Springer
Year
2003
Tongue
English
Weight
415 KB
Volume
59
Category
Article
ISSN
0031-6970

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## Abstract ## Objective Risperidone is converted to 9‐hydroxyrisperidone by CYP2D6. Two parameters were used to examine the influences of CYP2D6 polymorphism and of co‐medication on risperidone metabolism: the risperidone:9‐hydroxyrisperidone concentration ratio (R:9‐OHR ratio) and the sum of the