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P1A6 - Assessment of DNA damage in nurses handling anti-neoplastic agents by comet assay

✍ Scribed by Nurşen Başaran; Ülku Ündeǧer; Ayşe Kars


Book ID
119539893
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
126 KB
Volume
95
Category
Article
ISSN
0378-4274

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The single cell gel electrophoresis (SCGE) assay, or comet assay, is a highly sensitive method to measure DNA damage. The principle of the assay is based on the conversion of single-strand breaks and alkali-labile sites to double-strand breaks via alkaline lysis. The cells are subjected to electroph