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Assessment of reference values for DNA damage detected by the comet assay in human blood cell DNA

✍ Scribed by Peter Møller


Book ID
116760184
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
859 KB
Volume
612
Category
Article
ISSN
1383-5742

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The single cell gel electrophoresis (SCGE) assay, or comet assay, is a highly sensitive method to measure DNA damage. The principle of the assay is based on the conversion of single-strand breaks and alkali-labile sites to double-strand breaks via alkaline lysis. The cells are subjected to electroph