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p16INK4a-mediated suppression of telomerase in normal and malignant human breast cells

โœ Scribed by Alexey V. Bazarov; Marjolein Van Sluis; William C. Hines; Ekaterina Bassett; Alain Beliveau; Eric Campeau; Rituparna Mukhopadhyay; Won Jae Lee; Sonya Melodyev; Yuri Zaslavsky; Leonard Lee; Francis Rodier; Agustin Chicas; Scott W. Lowe; Jean Benhattar; Bing Ren; Judith Campisi; Paul Yaswen


Book ID
111199659
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
340 KB
Volume
9
Category
Article
ISSN
1474-9718

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## Abstract Prostate cancer is a major cause of cancer death among male population. Therefore, development of appropriate model systems is critical for understanding the molecular basis of prostate cancer progression. In this study, introduction of human telomerase (hTERT) into normal human prostat