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P13: Roles of cyclin A, PCNA and p21 in proliferation of the hepatic stellate cells in dimethylnitrosamine-induced rat hepatic fibrosis

✍ Scribed by Han-Seong Kim; Mi-Rhan Kim; Mi Sook Lee; In Pyung Chung; Ja-June Jang


Book ID
113608040
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
53 KB
Volume
61
Category
Article
ISSN
0940-2993

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Platelet-derived growth factor (PDGF) is the most potent mitogen for hepatic stellate cells (HSCs) in vitro. The aim of this study was to investigate the role of the lipid-derived second messenger phosphatidic acid (PA) in mediating this effect and, in particular, to determine its interaction with t