P.1.231 The brain-derived neurotrophic factor (BDNF) in bipolar affective disorder: A case-control association study
β Scribed by P. Oswald; D. Souery; J. Del-Favero; C. Van Broeckhoven; J. Mendlewicz
- Book ID
- 119576978
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 142 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0924-977X
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## Abstract Brainβderived neurotrophic factor (BDNF) is the most widely distributed neurotrophin in the central nervous system (CNS), and services many biological functions such as neural survival, differentiation, and plasticity. Previous studies have suggested that the Val66Met (also known as rs6
## Abstract Recent studies have indicated that the brainβderived neurotrophic factor (__BDNF__) gene is involved in the etiology of bipolar disorder (BPD). Two familyβbased association studies showed that the Val allele of the functional polymorphism Val66Met in the __BDNF__ gene is associated with