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P.1.06 Brain-derived neurotrophic factor (BDNF) gene in unipolar affective disorder: a Belgian patient-control association study

✍ Scribed by P. Oswald; J. Del-Favero; I. Massat; D. Souery; S. Claes; C. Van Broeckhoven; J. Mendlewicz

Book ID: 118590985
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 41 KB
Volume: 14
Category: Article
ISSN: 0924-977X
DOI: 10.1016/s0924-977x(04)90007-7

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## Abstract Several lines of evidence indicate an involvement of brain derived neurotrophic factor (BDNF) in body weight regulation and activity: heterozygous __Bdnf__ knockout mice (__Bdnf__^+/−^) are hyperphagic, obese, and hyperactive; furthermore, central infusion of BDNF leads to severe, dose‐