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P12. Vitamin D receptor expression and monocyte differentiation

✍ Scribed by Hewison, M.; Walker, R.; O'Riordan, J.L.H.

Book ID
122471781
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
173 KB
Volume
13
Category
Article
ISSN
8756-3282

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## Abstract 1,25‐dihydroxy vitamin D3 and 12‐O‐tetradecanoyl phorbol‐13‐acetate (TPA) interact synergistically to induce monocytic differentiation of U937 histiocytic lymphoma cells. Addition of TPA causes an otherwise ineffective dose of 1,25‐dihydroxy vitamin D3 to induce differentiation. The ind