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P104 Inhibition of platelet aggregation in vitro and in vivo by the H2S releasing compound GYY4137

✍ Scribed by Emerson, Michael; Solomon, Antonia; Smyth, Erica; Wood, Mark E.; Whiteman, Matthew


Book ID
124147085
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
42 KB
Volume
39
Category
Article
ISSN
1089-8603

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In vitro inhibition of rat platelet aggr
✍ Omar, Rabeea F. ;Randell, Edward ;Rahimtula, Anver D. πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 680 KB

The mycotoxin ochratoxin A (OA) consists of 5-chloro-3-methyl-3,4-dihydro-8-hydroxyisocoumarin moiety linked by an amide bond to p-Lphenylalanine. When added to washed rat platelets in vitro, OA caused a dose-dependent inhibition of aggregation induced by agonists such as adenosine diphosphate (ADP)