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Inhibition of platelet aggregation by myeloid leukaemic cells demonstrated in vitro

✍ Scribed by R. Fauldt; J. Ankerst; E. Zoucas


Book ID
114711098
Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
518 KB
Volume
66
Category
Article
ISSN
0007-1048

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In vitro inhibition of rat platelet aggr
✍ Omar, Rabeea F. ;Randell, Edward ;Rahimtula, Anver D. πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 680 KB

The mycotoxin ochratoxin A (OA) consists of 5-chloro-3-methyl-3,4-dihydro-8-hydroxyisocoumarin moiety linked by an amide bond to p-Lphenylalanine. When added to washed rat platelets in vitro, OA caused a dose-dependent inhibition of aggregation induced by agonists such as adenosine diphosphate (ADP)