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Inhibition of Leukocyte and Platelet Aggregation in vitro by Antithrombin

โœ Scribed by Donatella Gritti; Chiara Gasparetto; Angela Malinverno; G. Ricevuti

Book ID
114440467
Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
62 KB
Volume
29
Category
Article
ISSN
0303-8173

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In vitro inhibition of rat platelet aggr
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โœ Omar, Rabeea F. ;Randell, Edward ;Rahimtula, Anver D. ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 680 KB

The mycotoxin ochratoxin A (OA) consists of 5-chloro-3-methyl-3,4-dihydro-8-hydroxyisocoumarin moiety linked by an amide bond to p-Lphenylalanine. When added to washed rat platelets in vitro, OA caused a dose-dependent inhibition of aggregation induced by agonists such as adenosine diphosphate (ADP)