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P1-418 Lovastatin modulation of microglial activation via suppression of CD40 and its signaling pathway

✍ Scribed by Kirk P. Townsend; Dough Shytle; Nan Sun; Jin Zeng; Yun Bai; Martina Vendrame; Francisco Fernandez; David Morgan; Paul Sanberg; Jun Tan


Book ID
117413291
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
329 KB
Volume
25
Category
Article
ISSN
0197-4580

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## Abstract Recent studies have shown that the 3‐hydroxy‐3‐methylglutaryl coenzyme A reductase inhibitors (statins) possess antiinflammatory and immunomodulatory properties, distinct from their action of lowering serum lipid levels. Moreover, results of epidemiological studies suggest that long‐ter